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Study links Zoloft during pregnancy and birth defects

June 22nd, 2011

A study published by the New England Journal of Medicine in June 2007 found that women taking the antidepressant Zoloft during the early stages of pregnancy were twice as likely to give birth to a child with certain types of heart defects. The use of Zoloft while pregnant was also associated with an increased risk of other birth defects.

Women who took Zoloft during the first trimester of pregnancy were twice as likely to give birth to a child with left or right ventricular outflow tract defects, the study found. These women were also twice as likely to give birth to a child with septal defects when taking Zoloft early in pregnancy.

The study also concluded that Zoloft users were twice as likely to give birth to a child with craniosynostosis and six times as likely to give birth to a child with omphalocele. The use of Zoloft during pregnancy may also be linked to other types of birth defects, including hypoplastic left heart syndrome (HLHS).

Despite evidence linking Zoloft and birth defects, the Food and Drug Administration has not announced plans to issue a Zoloft recall. Women who gave birth to a child with birth defects may be eligible to file a Zoloft lawsuit if they took the antidepressant during pregnancy.

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