A new study in the British Journal of Clinical Pharmacology found that selective serotonin reuptake inhibitor (SSRI) antidepressants such as Zoloft could increase the risk of vehicle accidents. The study compared the drug use of more than 5,000 people involved in accidents with an additional 31,000 who were not in a wreck.
Drivers who were using an SSRI such as Zoloft were more likely to get into a wreck than drivers using other medications or no medication at all. This research adds to a long line of studies finding complications and side effects related to Zoloft use.
Most notably, Zoloft and other SSRIs have been linked to an increased risk of birth defects among women who use the drugs during pregnancy. Birth defects associated with Zoloft use include ventricular outflow heart defects and other congenital birth defects, including omphalocele (organs protruding from the belly button) and anencephaly (parts of the brain and skull missing).