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New drug treats depression without side effects of Zoloft

July 2nd, 2013

A drug molecularly related to ketamine treats many symptoms of depression without the negative effects of ketamine and sometimes life-threatening side effects of Zoloft. In a study published in the National Institute of Public Health, researchers found that GLYX-13 was a “molecular cousin” of ketamine, but did not have the same “street drug” side effects of ketamine.

GLYX-13 reportedly treated depression symptoms within one hour of ingestion and lasted all day, compared to selective serotonin reuptake inhibitors (SSRIs) such as Zoloft, which can take a longer time to take effect. The drug’s efficacy after one hour was nearly double that of Zoloft or other SSRI antidepressants at 6 weeks.

Zoloft side effects have caused many doctors and patients to question whether the drug’s benefits outweigh its risks. Zoloft birth defects have led women to file Zoloft lawsuits, alleging that the drug greatly increased their risk of giving birth to a child with heart defects, brain defects and other congenital birth defects.

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