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SSRIs could lead to abnormal bleeding

July 24th, 2013

A recent study has found that some patients who use selective serotonin reuptake inhibitor antidepressants (SSRIs) could be at an increased risk for abnormal bleeding. SSRI antidepressants include top-selling drugs such as Zoloft, Prozac, Celexa, Lexapro and Paxil.

The study, conducted by the Utrecht Institute for Pharmaceutical Studies in the Netherlands, involved more than 64,000 patients on SSRIs. Researchers found that patients on antidepressants were more likely to require hospitalization for bleeding, such as gastrointestinal bleeding and bleeding in the uterus. There was a correlation between the strength of the SSRI and the amount of bleeding.

Antidepressants side effects have become a primary focus for researchers, particularly SSRI birth defects. Women who use SSRIs during pregnancy have been shown to be at an increased risk of giving birth to a child with heart defects, brain defects and other congenital birth defects.

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