Selective serotonin reuptake inhibitor antidepressants (SSRIs) such as Zoloft may have been accepted into the medical community due to publication bias, studies show. Recent studies concerning Zoloft side effects have since put the antidepressants under a scrutiny, including severe Zoloft birth defects.
A New England Journal of Medicine review found that a vast majority of information concerning SSRI antidepressants originally went unpublished. While published articles found a 94% efficacy rate for SSRIs, unpublished articles brought that rate to just over 50%, while citing potential health concerns and SSRI side effects.
Zoloft manufacturer Pfizer is facing several Zoloft birth defect lawsuits alleging that the drug caused birth defects in children born to women who used it. Zoloft birth defects include heart defects, brain defects, omphalocele, anencephaly, cleft defects and other congenital birth defects.